BBMRI-OMICS

BBMRI-Omics is the joint collection of omics data that has collaboratively been generated and that is made available for BBMRI researchers focusing on integrative omics studies in Dutch Biobanks.

BBMRI-Omics Warehouse with available data resources


DNA Genetic Variation has been generated within the Genome of the Netherlands (GoNL) consortium using Whole Genome Sequencing with Illumina Hiseq technology.

Gene expression data has been generated within the Biobank-based Integrative Omics Studies Consortium (BIOS) consortium using Illumina RNA sequencing technology.

DNA methylation data has been generated within the Biobank-based Integrative Omics Studies Consortium (BIOS) consortium using Illumina 450K array technology.

Metabolomics data has been generated within the Metabolomics Consortium using the Nightingale Health (formerly Brainshake) technology.

In the future, BBMRI-Omics intend to extend the collection of omics data with MRI imaging data and gut microbiome data.

 

Mission

The mission of BBMRI-Omics is to create a large-scale data infrastructure and to bring together BBMRI researchers focusing on integrative omics studies in Dutch Biobanks. Currently over 23 Dutch cohorts are sharing their data within BBMRI-Omics, which consists of omics data in over 26,000 samples.

 

Explore data available for analysis: https://omics-explorer.bbmri.nl/

 

 

Browse results of previous analyses: http://bbmri.researchlumc.nl/atlas/

Browse results of previous analyses

 

 

Access to BBMRI-Omics data using a centralized computational facility

In the near future we will have 1 data access procedure, but currently you still have to follow the separate data access procedures:

For access to the Whole Genome Sequencing data, please go to the GoNL page.

For access to Gene Expression or DNA methylation data, please go to the BIOS consortium page.

For access to the Metabolomics data, please go to the Metabolomics Consortium page.

 

Wiki

The BBMRI BIOS consortium has in parallel with the Metabolomics Consortium generated DNA Methylation and Gene expression data. At the wiki http://wiki.bbmri.nl/wiki/BIOS_start-  which is created by the BBMRI BIOS consortium you can also find all the information concerning data requests, access and processing.

 

BBMRI-Omics Management Team

Marian Beekman1, Bastiaan T. Heijmans1, Joyce van Meurs2, Lude Franke3, Marleen van Greevenbroek4, Arfan Ikram5, Dorret I. Boomsma6, P. Eline Slagboom1

 

1.Molecular Epidemiology, LUMC, Leiden

2.Internal Medicine, Erasmus University Medical Center, Rotterdam

3.Genetics, University Medical Center Groningen, University of Groningen, Groningen

4.Internal Medicine, School for Cardiovascular Diseases, Fac. Health, Medicine and Life Sciences, Maastricht University, Maastricht

5.Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam

6.Biological Psychology, Vrije Universiteit, Amsterdam

 

Update: 9 October 2018