Scientific publications 2019

Below you will find an overview of BBMRI-NL Scientific publications in peer reviewed journals. We have only listed items that contain BBMRI-NL or the grant number in the affiliation, funding and/or acknowledgement section of the article. Items are listed per year in alphabetical order.
  • 't Hart, L.S., E; Rutters, F; van der Heijden, AA; Nijpels, G; Elders, PJ; Beulens, JW; Slieker, RC (2019). Metabolomic measurements are associated with glycaemic control and progression of type 2 diabetes: a BBMRI-NL metabolomics study. Diabetologia 62, S97-S98.
  • Abdellaoui, A., Sanchez-Roige, S., Sealock, J., Treur, J.L., Dennis, J., Fontanillas, P., et al. (2019). Phenome-wide investigation of health outcomes associated with genetic predisposition to loneliness. Hum Mol Genet 28(22), 3853-3865. doi: 10.1093/hmg/ddz219.
  • Acevedo-Mesa, A., Rosmalen, J.G.M., Ranchor, A.V., and Roest, A.M. (2019). Positive affect and functional somatic symptoms in young adults. J Psychosom Res 127, 109847. doi: 10.1016/j.jpsychores.2019.109847.
  • Ahluwalia, T.T., N; Vogelzangs, N; Mook-Kanamori, D; Brahimaj, A; Frimodt-Moller, M; Arts, I; Beulens, J; van der Heijden, A; Stehouwer, C; Nijpels, G; van Greevenbroek, M; van der Kallen, C; Rossing, P; 't Hart, LM (2019). Plasma metabolomics identifies markers of kidney function in 3,064 Europeans with type 2 diabetes. Diabetologia 62, S456.
  • Arias-Vasquez, A., Groffen, A.J., Spijker, S., Ouwens, K.G., Klein, M., Vojinovic, D., et al. (2019). A Potential Role for the STXBP5-AS1 Gene in Adult ADHD Symptoms. Behav Genet 49(3), 270-285. doi: 10.1007/s10519-018-09947-2.
  • Barzeva, S.A., Meeus, W.H.J., and Oldehinkel, A.J. (2019). Social Withdrawal in Adolescence and Early Adulthood: Measurement Issues, Normative Development, and Distinct Trajectories. J Abnorm Child Psychol 47(5), 865-879. doi: 10.1007/s10802-018-0497-4.
  • Baselmans, B.M.L., van de Weijer, M.P., Abdellaoui, A., Vink, J.M., Hottenga, J.J., Willemsen, G., et al. (2019). A Genetic Investigation of the Well-Being Spectrum. Behav Genet 49(3), 286-297. doi: 10.1007/s10519-019-09951-0.
  • Bell, C.G., Lowe, R., Adams, P.D., Baccarelli, A.A., Beck, S., Bell, J.T., et al. (2019). DNA methylation aging clocks: challenges and recommendations. Genome Biol 20(1), 249. doi: 10.1186/s13059-019-1824-y.
  • de Bruine, M., Giletta, M., Denissen, J.J.A., Sijtsema, J.J., and Oldehinkel, A.J. (2019). A healthy peer status: Peer preference, not popularity, predicts lower systemic inflammation in adolescence. Psychoneuroendocrinology 109, 104402. doi: 10.1016/j.psyneuen.2019.104402.
  • Deelen, J., Kettunen, J., Fischer, K., van der Spek, A., Trompet, S., Kastenmuller, G., et al. (2019a). A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals. Nat Commun 10(1), 3346. doi: 10.1038/s41467-019-11311-9.
  • Deelen, P., van Dam, S., Herkert, J.C., Karjalainen, J.M., Brugge, H., Abbott, K.M., et al. (2019b). Improving the diagnostic yield of exome- sequencing by predicting gene-phenotype associations using large-scale gene expression analysis. Nat Commun 10(1), 2837. doi: 10.1038/s41467-019-10649-4.
  • Finnicum, C.T., Beck, J.J., Dolan, C.V., Davis, C., Willemsen, G., Ehli, E.A., et al. (2019). Cohabitation is associated with a greater resemblance in gut microbiota which can impact cardiometabolic and inflammatory risk. BMC Microbiol 19(1), 230. doi: 10.1186/s12866-019-1602-8.
  • Generaal, E., Hoogendijk, E.O., Stam, M., Henke, C.E., Rutters, F., Oosterman, M., et al. (2019). Neighbourhood characteristics and prevalence and severity of depression: pooled analysis of eight Dutch cohort studies. Br J Psychiatry 215(2), 468-475. doi: 10.1192/bjp.2019.100.
  • Goisauf, M., Martin, G., Bentzen, H.B., Budin-Ljosne, I., Ursin, L., Durnova, A., et al. (2019). Data in question: A survey of European biobank professionals on ethical, legal and societal challenges of biobank research. PLoS One 14(9), e0221496. doi: 10.1371/journal.pone.0221496.
  • Groen, R.N., Wichers, M., Wigman, J.T.W., and Hartman, C.A. (2019). Specificity of psychopathology across levels of severity: a transdiagnostic network analysis. Sci Rep 9(1), 18298. doi: 10.1038/s41598-019-54801-y.
  • Gruzieva, O., Xu, C.J., Yousefi, P., Relton, C., Merid, S.K., Breton, C.V., et al. (2019). Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis. Environ Health Perspect 127(5), 57012. doi: 10.1289/EHP4522.
  • Hartman, C.A., Rommelse, N., van der Klugt, C.L., Wanders, R.B.K., and Timmerman, M.E. (2019). Stress Exposure and the Course of ADHD from Childhood to Young Adulthood: Comorbid Severe Emotion Dysregulation or Mood and Anxiety Problems. J Clin Med 8(11). doi: 10.3390/jcm8111824.
  • Jahanshad, N., Faskowitz, J., Roshchupkin, G., Hibar, D.P., Gutman, B.A., Tustison, N.J., et al. (2019). Multi-Site Meta-Analysis of Morphometry. IEEE/ACM Trans Comput Biol Bioinform 16(5), 1508-1514. doi: 10.1109/TCBB.2019.2914905.
  • Ligthart, L., van Beijsterveldt, C.E.M., Kevenaar, S.T., de Zeeuw, E., van Bergen, E., Bruins, S., et al. (2019). The Netherlands Twin Register: Longitudinal Research Based on Twin and Twin-Family Designs. Twin Res Hum Genet 22(6), 623-636. doi: 10.1017/thg.2019.93.
  • Maas, S.C.E., Vidaki, A., Wilson, R., Teumer, A., Liu, F., van Meurs, J.B.J., et al. (2019). Validated inference of smoking habits from blood with a finite DNA methylation marker set. Eur J Epidemiol 34(11), 1055-1074. doi: 10.1007/s10654-019-00555-w.
  • Mbarek, H., van Beijsterveldt, C.E.M., Jan Hottenga, J., Dolan, C.V., Boomsma, D.I., Willemsen, G., et al. (2019). Association Between rs1051730 and Smoking During Pregnancy in Dutch Women. Nicotine Tob Res 21(6), 835-840. doi: 10.1093/ntr/ntx267.
  • Michielsen, C., Hangelbroek, R.W.J., Feskens, E.J.M., and Afman, L.A. (2019). Disentangling the Effects of Monounsaturated Fatty Acids from Other Components of a Mediterranean Diet on Serum Metabolite Profiles: A Randomized Fully Controlled Dietary Intervention in Healthy Subjects at Risk of the Metabolic Syndrome. Mol Nutr Food Res 63(9), e1801095. doi: 10.1002/mnfr.201801095.
  • Milaneschi, Y., Peyrot, W.J., Nivard, M.G., Mbarek, H., Boomsma, D.I., and B, W.J.H.P. (2019). A role for vitamin D and omega-3 fatty acids in major depression? An exploration using genomics. Transl Psychiatry 9(1), 219. doi: 10.1038/s41398-019-0554-y.
  • Mishra, A., Chauhan, G., Violleau, M.H., Vojinovic, D., Jian, X., Bis, J.C., et al. (2019). Association of variants in HTRA1 and NOTCH3 with MRI-defined extremes of cerebral small vessel disease in older subjects. Brain 142(4), 1009-1023. doi: 10.1093/brain/awz024.
  • Onderwater, G.L.J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., van der Kallen, C.J.H., et al. (2019). Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology 92(16), e1899-e1911. doi: 10.1212/WNL.0000000000007313.
  • Ong, J., Faiz, A., Timens, W., van den Berge, M., Terpstra, M.M., Kok, K., et al. (2019). Marked TGF-beta-regulated miRNA expression changes in both COPD and control lung fibroblasts. Sci Rep 9(1), 18214. doi: 10.1038/s41598-019-54728-4.
  • Peeters, M., Oldehinkel, A., Veenstra, R., and Vollebergh, W. (2019). Unique developmental trajectories of risk behaviors in adolescence and associated outcomes in young adulthood. PLoS One 14(11), e0225088. doi: 10.1371/journal.pone.0225088.
  • Richards, J.S., Hartman, C.A., Jeronimus, B.F., Ormel, J., Reijneveld, S.A., Veenstra, R., et al. (2019). Beyond not bad or just okay: social predictors of young adults' wellbeing and functioning (a TRAILS study). Psychol Med 49(9), 1459-1469. doi: 10.1017/S0033291718001976.
  • Sanna, S., van Zuydam, N.R., Mahajan, A., Kurilshikov, A., Vich Vila, A., Vosa, U., et al. (2019). Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases. Nat Genet 51(4), 600-605. doi: 10.1038/s41588-019-0350-x.
  • Smarius, L., Strieder, T.G.A., Doreleijers, T.A.H., Vrijkotte, T.G.M., Zafarmand, M.H., and de Rooij, S.R. (2019). Common oxytocin polymorphisms interact with maternal verbal aggression in early infancy impacting blood pressure at age 5-6: The ABCD study. PLoS One 14(6), e0216035. doi: 10.1371/journal.pone.0216035.
  • Stahl, E.A., Breen, G., Forstner, A.J., McQuillin, A., Ripke, S., Trubetskoy, V., et al. (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat Genet 51(5), 793-803. doi: 10.1038/s41588-019-0397-8.
  • Tilot, A.K., Vino, A., Kucera, K.S., Carmichael, D.A., van den Heuvel, L., den Hoed, J., et al. (2019). Investigating genetic links between grapheme-colour synaesthesia and neuropsychiatric traits. Philos Trans R Soc Lond B Biol Sci 374(1787), 20190026. doi: 10.1098/rstb.2019.0026.
  • van de Putte, R., Wijers, C.H.W., Reutter, H., Vermeulen, S.H., Marcelis, C.L.M., Brosens, E., et al. (2019). Exome chip association study excluded the involvement of rare coding variants with large effect sizes in the etiology of anorectal malformations. PLoS One 14(5), e0217477. doi: 10.1371/journal.pone.0217477.
  • van der Jagt-Jelsma, W.d.V.-S., MR; Klip, H; van Deurzen, PAM; Buitelaar, JK (2019). The Association between Parental Religiosity, Stressful Life Events, and Problem Behaviour in Pre-adolescents and Adolescents European Journal of Mental Health 14(2), 296-310.
  • van der Laan, T., Kloots, T., Beekman, M., Kindt, A., Dubbelman, A.C., Harms, A., et al. (2019). Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum. Sci Rep 9(1), 12370. doi: 10.1038/s41598-019-48876-w.
  • van der Spek, A., Broer, L., Draisma, H.H.M., Pool, R., Albrecht, E., Beekman, M., et al. (2019). Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium. Sci Rep 9(1), 11623. doi: 10.1038/s41598-019-47282-6.
  • van Dongen, J., Zilhao, N.R., Sugden, K., Consortium, B., Hannon, E.J., Mill, J., et al. (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biol Psychiatry 86(8), 599-607. doi: 10.1016/j.biopsych.2019.02.016.
  • van Laarhoven, C., van Setten, J., van Herwaarden, J.A., Pasterkamp, G., de Kleijn, D.P.V., de Borst, G.J., et al. (2019). Polygenic Susceptibility of Aortic Aneurysms Associates to the Diameter of the Aneurysm Sac: the Aneurysm-Express Biobank Cohort. Sci Rep 9(1), 19844. doi: 10.1038/s41598-019-56230-3.
  • van Rooij, J., Mandaviya, P.R., Claringbould, A., Felix, J.F., van Dongen, J., Jansen, R., et al. (2019). Evaluation of commonly used analysis strategies for epigenome- and transcriptome-wide association studies through replication of large-scale population studies. Genome Biol 20(1), 235. doi: 10.1186/s13059-019-1878-x.
  • Vojinovic, D., Radjabzadeh, D., Kurilshikov, A., Amin, N., Wijmenga, C., Franke, L., et al. (2019). Relationship between gut microbiota and circulating metabolites in population-based cohorts. Nat Commun 10(1), 5813. doi: 10.1038/s41467-019-13721-1.
  • Willemse, E.A.J., Vermeiren, Y., Garcia-Ayllon, M.S., Bridel, C., De Deyn, P.P., Engelborghs, S., et al. (2019). Pre-analytical stability of novel cerebrospinal fluid biomarkers. Clin Chim Acta 497, 204-211. doi: 10.1016/j.cca.2019.07.024.
  • Abdellaoui, A., Chen, H.Y., Willemsen, G., Ehli, E.A., Davies, G.E., Verweij, K.J.H., Nivard, M.G., de Geus, E.J.C., Boomsma, D.I., and Cacioppo, J.T. (2019). Associations between loneliness and personality are mostly driven by a genetic association with Neuroticism. J Pers 87, 386-397.
  • Baselmans, B.M.L., Jansen, R., Ip, H.F., van Dongen, J., Abdellaoui, A., van de Weijer, M.P., Bao, Y., Smart, M., Kumari, M., Willemsen, G., et al. (2019). Multivariate genome-wide analyses of the well-being spectrum. Nat Genet 51, 445-451.
  • de Geus, E.J.C., Gianaros, P.J., Brindle, R.C., Jennings, J.R., and Berntson, G.G. (2019). Should heart rate variability be "corrected" for heart rate? Biological, quantitative, and interpretive considerations. Psychophysiology 56, e13287.
  • Eisenga, M.F., Wouters, H., Kieneker, L.M., van der Klauw, M.M., van der Meer, P., Wolffenbuttel, B.H.R., Gaillard, C., Kootstra-Ros, J.E., Touw, D.J., Huls, G., et al. (2019). Active smoking and macrocytosis in the general population: Two population-based cohort studies. Am J Hematol 94, E45-E48.
  • Ferreira, M.A.R., Mathur, R., Vonk, J.M., Szwajda, A., Brumpton, B., Granell, R., Brew, B.K., Ullemar, V., Lu, Y., Jiang, Y., et al. (2019). Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct. Am J Hum Genet 104, 665-684.
  • Fiorito, G., McCrory, C., Robinson, O., Carmeli, C., Rosales, C.O., Zhang, Y., Colicino, E., Dugue, P.A., Artaud, F., McKay, G.J., et al. (2019). Socioeconomic position, lifestyle habits and biomarkers of epigenetic aging: a multi-cohort analysis. Aging 11, 2045-2070.
  • Hamalainen, I., Tornwall, O., Simell, B., Zatloukal, K., Perola, M., and van Ommen, G.B. (2019). Role of Academic Biobanks in Public-Private Partnerships in the European Biobanking and BioMolecular Resources Research Infrastructure Community. Biopreserv Biobank 17, 46-51.
  • Kaufman, T.M.L., Baams, L., and Veenstra, R. (2019). Disparities in Persistent Victimization and Associated Internalizing Symptoms for Heterosexual Versus Sexual Minority Youth. J Res Adolesc.
  • Lee, M.K., Xu, C.J., Carnes, M.U., Nichols, C.E., Ward, J.M., consortium, B., Kwon, S.O., Kim, S.Y., Kim, W.J., and London, S.J. (2019). Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults. Clin Epigenetics 11, 37.
  • Michielsen, C., Hangelbroek, R.W.J., Feskens, E.J.M., and Afman, L.A. (2019). Disentangling the Effects of Monounsaturated Fatty Acids from Other Components of a Mediterranean Diet on Serum Metabolite Profiles: A Randomized Fully Controlled Dietary Intervention in Healthy Subjects at Risk of the Metabolic Syndrome. Mol Nutr Food Res 63, e1801095.
  • Moore, R., Casale, F.P., Jan Bonder, M., Horta, D., Consortium, B., Franke, L., Barroso, I., and Stegle, O. (2019). A linear mixed-model approach to study multivariate gene-environment interactions. Nat Genet 51, 180-186.
  • Onderwater, G.L.J., Ligthart, L., Bot, M., Demirkan, A., Fu, J., van der Kallen, C.J.H., Vijfhuizen, L.S., Pool, R., Liu, J., Vanmolkot, F.H.M., et al. (2019). Large-scale plasma metabolome analysis reveals alterations in HDL metabolism in migraine. Neurology 92, e1899-e1911.
  • Pastorino, S., Bishop, T., Crozier, S.R., Granstrom, C., Kordas, K., Kupers, L.K., O'Brien, E.C., Polanska, K., Sauder, K.A., Zafarmand, M.H., et al. (2019). Associations between maternal physical activity in early and late pregnancy and offspring birth size: remote federated individual level meta-analysis from eight cohort studies. BJOG 126, 459-470.
  • Schlicht, K., Nyczka, P., Caliebe, A., Freitag-Wolf, S., Claringbould, A., Franke, L., Vosa, U., Consortium, B., Kardia, S.L.R., Smith, J.A., et al. (2019). The metabolic network coherence of human transcriptomes is associated with genetic variation at the cadherin 18 locus. Hum Genet 138, 375-388.
  • Shvetsova, E., Sofronova, A., Monajemi, R., Gagalova, K., Draisma, H.H.M., White, S.J., Santen, G.W.E., Chuva de Sousa Lopes, S.M., Heijmans, B.T., van Meurs, J., et al. (2019). Skewed X-inactivation is common in the general female population. Eur J Hum Genet 27, 455-465.
  • Simell, B.A., Tornwall, O.M., Hamalainen, I., Wichmann, H.E., Anton, G., Brennan, P., Bouvard, L., Slimani, N., Moskal, A., Gunter, M., et al. (2019). Transnational access to large prospective cohorts in Europe: Current trends and unmet needs. N Biotechnol 49, 98-103.
  • Smarius, L., Strieder, T.G.A., Doreleijers, T.A.H., Vrijkotte, T.G.M., Zafarmand, M.H., and de Rooij, S.R. (2019). Maternal verbal aggression in early infancy and child's internalizing symptoms: interaction by common oxytocin polymorphisms. Eur Arch Psychiatry Clin Neurosci.
  • Stahl, E.A., Breen, G., Forstner, A.J., McQuillin, A., Ripke, S., Trubetskoy, V., Mattheisen, M., Wang, Y., Coleman, J.R.I., Gaspar, H.A., et al. (2019). Genome-wide association study identifies 30 loci associated with bipolar disorder. Nat Genet 51, 793-803.
  • van Dongen, J., Zilhao, N.R., Sugden, K., Consortium, B., Hannon, E.J., Mill, J., Caspi, A., Agnew-Blais, J., Arseneault, L., Corcoran, D.L., et al. (2019). Epigenome-wide Association Study of Attention-Deficit/Hyperactivity Disorder Symptoms in Adults. Biol Psychiatry.