Publications 2014

We have listed only items that contain BBMRI-NL or the grant number in the affiliation, funding and/or acknowledgement section of the article. Items are listed per year in alphabetical order.

  • Agarwal, D., Pineda, S., Michailidou, K., Herranz, J., Pita, G., Moreno, L.T., Alonso, M.R., Dennis, J., Wang, Q., Bolla, M.K., et al. (2014). FGF receptor genes and breast cancer susceptibility: results from the Breast Cancer Association Consortium. British Journal of Cancer 110, 1088-1100.

  • Akker van den, E.B., Passtoors, W.M., Jansen, R., van Zwet, E.W., Goeman, J.J., Hulsman, M., Emilsson, V., Perola, M., Willemsen, G., Penninx, B.W.J.H., et al. (2014). Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein- protein interaction modules as robust markers of human aging. Aging Cell 13, 216-225.

  • Ali, A.M.G., Schmidt, M.K., Bolla, M.K., Wang, Q., Gago-Dominguez, M., Castelao, J.E., Carracedo, A., Garzon, V.M., Bojesen, S.E., Nordestgaard, B.G., et al. (2014). Alcohol consumption and survival after a breast cancer diagnosis: a literature-based meta-analysis and collaborative analysis of data for 29,239 cases. Cancer Epidemiology Biomarkers & Prevention 23, 934-945.

  • Almeida, R., Ricano-Ponce, I., Kumar, V., Deelen, P., Szperl, A., Trynka, G., Gutierrez-Achury, J., Kanterakis, A., Westra, H.J., Franke, L., et al. (2014). Fine mapping of the celiac disease-associated LPP locus reveals a potential functional variant. Human Molecular Genetics 23, 2481-2489.

  • Ariel, A., Bakker, B., de Groot, M., van Grootheest, G., van der Laan, J., Smit, J., and Verkerk, B. (2014). Record linkage in health data: a simulation study (https://www.cbs.nl/nl-nl/achtergrond/2014/16/record-linkage-in-health-data-a-simulation-study), pp. https://www.cbs.nl/nl-nl/achtergrond/2014/2016/record-linkage-in-health-data-a-simulation-study.

  • Bardai, A., Blom, M.T., van Hoeijen, D.A., van Deutekom, H.W.M., Brouwer, H.J., and Tan, H.L. (2014). Atrial Fibrillation Is an Independent Risk Factor for Ventricular Fibrillation A Large-Scale Population-Based Case-Control Study. Circulation - Arrhythmia and Electrophysiology 7, 1033-1039.

  • Battes, L.C., Akkerhuis, K.M., Cheng, J.M., Garcia-Garcia, H.M., Oemrawsingh, R.M., de Boer, S.P.M., Regar, E., van Geuns, R.J., Serruys, P.W., Boersma, E., et al. (2014a). Circulating acute phase proteins in relation to extent and composition of coronary atherosclerosis and cardiovascular outcome: Results from the ATHEROREMO-IVUS study. International Journal of Cardiology 177, 847-853.

  • Battes, L.C., Cheng, J.M., Oemrawsingh, R.M., Boersma, E., Garcia-Garcia, H.M., de Boer, S.P., Buljubasic, N., Mieghem, N.A., Regar, E., Geuns, R.J., et al. (2014b). Circulating cytokines in relation to the extent and composition of coronary atherosclerosis: results from the ATHEROREMO-IVUS study. Atherosclerosis 236, 18-24.

  • Benke, K.S., Nivard, M.G., Velders, F.P., Walters, R.K., Pappa, I., Scheet, P.A., Xiao, X., Ehli, E.A., Palmer, L.J., Whitehouse, A.J., et al. (2014). A genome-wide association meta-analysis of preschool internalizing problems. J Am Acad Child Adolesc Psychiatry 53, 667-676.

  • Bennik, E.C., Nederhof, E., Ormel, J., and Oldehinkel, A.J. (2014). Anhedonia and depressed mood in adolescence: course, stability, and reciprocal relation in the TRAILS study. European Child & Adolescent Psychiatry 23, 579-586.

  • Blom, M.T., Beesems, S.G., Homma, P.C.M., Zijlstra, J.A., Hulleman, M., van Hoeijen, D.A., Bardai, A., Tijssen, J.G.P., Tan, H.L., and Koster, R.W. (2014a). Improved Survival After Out-of-Hospital Cardiac Arrest and Use of Automated External Defibrillators. Circulation 130, 1868-1875.

  • Blom, M.T., Cohen, D., Seldenrijk, A., Penninx, B.W.J.H., Nijpels, G., Stehouwer, C.D.A., Dekker, J.M., and Tan, H.L. (2014b). Brugada Syndrome ECG Is Highly Prevalent in Schizophrenia. Circulation - Arrhythmia and Electrophysiology 7, 384-391.

  • Blom, M.T., van Hoeijen, D.A., Bardai, A., Berdowski, J., Souverein, P.C., de Bruin, M.L., Koster, R.W., de Boer, A., and Tan, H.L. (2014c). Genetic, clinical and pharmacological determinants of out-of-hospital cardiac arrest: rationale and outline of the AmsteRdam Resuscitation Studies (ARREST) registry. Open Heart 1, e000112.

  • Boeckhout, M., Reuzel, R., Zielhuis, G.A., Vermeulen, E., Schmidt, M.K., and Janssens, A.C.J.W. (2014a). De donor als partner : Hoe patiënt en publiek te betrekken bij besluitvorming over biobanken en registraties (BBMRI-NL; RP6 Towards a joint strategy for the return of results and optimal communication with biobank donors).

  • Boeckhout, M., Reuzel, R., Zielhuis, G.A., Vermeulen, E., Schmidt, M.K., and Janssens, A.C.J.W. (2014b). The donor as partner: How to involve patients and the public in the governance of biobanks and registries (BBMRI-NL; RP6 Towards a joint strategy for the return of results and optimal communication with biobank donors).

  • Boelema, S.R., Harakeh, Z., Ormel, J., Hartman, C.A., Vollebergh, W.A.M., and van Zandvoort, M.J.E. (2014). Executive functioning shows differential maturation from early to late adolescence: longitudinal findings from a TRAILS study. Neuropsychology 28, 177-187.

  • Bonder, M.J., Kasela, S., Kals, M., Tamm, R., Lokk, K., Barragan, I., Buurman, W.A., Deelen, P., Greve, J.W., Ivanov, M., et al. (2014). Genetic and epigenetic regulation of gene expression in fetal and adult human livers. BMC Genomics 15, article nr: 860.

  • Boomsma, D.I., Wijmenga, C., Slagboom, E.P., Swertz, M.A., Karssen, L.C., Abdellaoui, A., Ye, K., Guryev, V., Vermaat, M., van Dijk, F., et al. (2014). The Genome of the Netherlands: design, and project goals. Eur J Hum Genet 22, 221-227.

  • Boudewijn, I.M., Savenije, O.E., Koppelman, G.H., Wijga, A.H., Smit, H.A., de Jongste, J.C., Gehring, U., Postma, D.S., and Kerkhof, M. (2014). Nocturnal dry cough in the first 7 years of life is associated with asthma at school age. Pediatric Pulmonology 50, 848-855.

  • Broer, L., Raschenberger, J., Deelen, J., Mangino, M., Codd, V., Pietilainen, K.H., Albrecht, E., Amin, N., Beekman, M., de Craen, A.J.M., et al. (2014). Association of adiponectin and leptin with relative telomere length in seven independent cohorts including 11,448 participants. European Journal of Epidemiology 29, 629-638.

  • Byrne, E.M., Carrillo-Roa, T., Penninx, B.W.J.H., Sallis, H.M., Viktorin, A., Chapman, B., Henders, A.K., Pergadia, M.L., Heath, A.C., Madden, P.A.F., et al. (2014). Applying polygenic risk scores to postpartum depression. Archives of Womens Mental Health 17, 519-528.

  • Cai, D.C., Fonteijn, H., Guadalupe, T., Zwiers, M., Wittfeld, K., Teumer, A., Hoogman, M., Arias-Vasquez, A., Yang, Y., Buitelaar, J., et al. (2014). A genome-wide search for quantitative trait loci affecting the cortical surface area and thickness of Heschl's gyrus. Genes Brain and Behavior 13, 675-685.

  • Chen, J.Y., Liu, J.Y., Calhoun, V.D., Arias-Vasquez, A., Zwiers, M.P., Gupta, C.N., Franke, B., and Turner, J.A. (2014). Exploration of scanning effects in multi-site structural MRI studies. Journal of Neuroscience Methods 230, 37-50.

  • Cornelis, M.C., Byrne, E.M., Esko, T., Nalls, M.A., Ganna, A., Paynter, N., Monda, K.L., Amin, N., Fischer, K., Renstrom, F., et al. (2014). Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption. Molecular Psychiatry 20, 647-656.

  • Cousijn, H., Eissing, M., Fernandez, G., Fisher, S.E., Franke, B., Zwiers, M., Harrison, P.J., and Arias-Vasquez, A. (2014). No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure. Schizophrenia Research 159, 329-332.

  • Dane, A.D., Hendriks, M.M., Reijmers, T.H., Harms, A.C., Troost, J., Vreeken, R.J., Boomsma, D.I., van Duijn, C.M., Slagboom, E.P., and Hankemeier, T. (2014). Integrating metabolomics profiling measurements across multiple biobanks. Analytical chemistry 86, 4110-4114.

  • Davies, J.R., Field, S., Randerson-Moor, J., Harland, M., Kumar, R., Anic, G.M., Nagore, E., Hansson, J., Hoiom, V., Jonsson, G., et al. (2014a). An inherited variant in the gene coding for vitamin D-binding protein and survival from cutaneous melanoma: a BioGenoMEL study. Pigment Cell Melanoma Res 27, 234-243.

  • Davies, J.R., Jewell, R., Affleck, P., Anic, G.M., Randerson-Moor, J., Ozola, A., Egan, K.M., Elliott, F., Garcia-Casado, Z., Hansson, J., et al. (2014b). Inherited variation in the PARP1 gene and survival from melanoma. International Journal of Cancer 135, 1625-1633.

  • Deelen, J., Beekman, M., Codd, V., Trompet, S., Broer, L., Hagg, S., Fischer, K., Thijssen, P.E., Suchiman, H.E.D., Postmus, I., et al. (2014a). Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers. International Journal of Epidemiology 43, 878-886.

  • Deelen, J., Beekman, M., Uh, H.W., Broer, L., Ayers, K.L., Tan, Q., Kamatani, Y., Bennet, A.M., Tamm, R., Trompet, S., et al. (2014b). Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age. Human Molecular Genetics 23, 4420-4432.

  • Deelen, P., Bonder, M.J., van der Velde, K.J., Westra, H.J., Winder, E., Hendriksen, D., Franke, L., and Swertz, M.A. (2014c). Genotype harmonizer: automatic strand alignment and format conversion for genotype data integration. BMC Research Notes 7, 901.

  • Deelen, P., Menelaou, A., van Leeuwen, E.M., Kanterakis, A., van Dijk, F., Medina-Gomez, C., Francioli, L.C., Hottenga, J.J., Karssen, L.C., Estrada, K., et al. (2014d). Improved imputation quality of low-frequency and rare variants in European samples using the 'Genome of The Netherlands'. European Journal of Human Genetics 22, 1321-1326.

  • Dekker, L.P., Hartman, C.A., van der Vegt, E.J., Verhulst, F.C., van Oort, F.V., and Greaves-Lord, K. (2014). The longitudinal relation between childhood autistic traits and psychosexual problems in early adolescence: The Tracking Adolescents' Individual Lives Survey study. Autism 19, 684-693.

  • Dijkstra, A.E., Smolonska, J., van den Berge, M., Wijmenga, C., Zanen, P., Luinge, M.A., Platteel, M., Lammers, J.W., Dahlback, M., Tosh, K., et al. (2014a). Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One 9, e91621.

  • Dijkstra, J.K., Kretschmer, T., Lindenberg, S., and Veenstra, R. (2014b). Hedonic, instrumental, and normative motives: Differentiating patterns for popular, accepted, and rejected adolescents. The Journal of Early Adolescence 35, 308-328.

  • Dongen van, J., Jansen, R., Smit, D., Hottenga, J.J., Mbarek, H., Willemsen, G., Kluft, C., Penninx, B.W.J.H., Ferreira, M.A., Boomsma, D.I., et al. (2014). The Contribution of the Functional IL6R Polymorphism rs2228145, eQTLs and Other Genome-Wide SNPs to the Heritability of Plasma sIL-6R Levels. Behavior Genetics 44, 368-382.

  • Drukker, C.A., Schmidt, M.K., Rutgers, E.J.T., Cardoso, F., Kerlikowske, K., Esserman, L.J., van Leeuwen, F.E., Pijnappel, R.M., Slaets, L., Bogaerts, J., et al. (2014a). Mammographic screening detects low-risk tumor biology breast cancers. Breast Cancer Research and Treatment 144, 103-111.

  • Drukker, C.A., Tinteren, H., Schmidt, M.K., Rutgers, E.J.T., Bernards, R., Vijver, M.J., and van 't Veer, L.J. (2014b). Long-term impact of the 70-gene signature on breast cancer outcome. Breast Cancer Research and Treatment 143, 587-592.

  • Drukker, C.A., van den Hout, H.C., Sonke, G.S., Brain, E., Bonnefoi, H., Cardoso, F., Goldhirsch, A., Harbeck, N., Honkoop, A.H., Koornstra, R.H.T., et al. (2014c). Risk estimations and treatment decisions in early stage breast cancer: Agreement among oncologists and the impact of the 70-gene signature. European Journal of Cancer 50, 1045-1054.

  • Forouhi, N.G., Koulman, A., Sharp, S.J., Imamura, F., Kroger, J., Schulze, M.B., Crowe, F.L., Huerta, J.M., Guevara, M., Beulens, J.W.J., et al. (2014). Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study. Lancet Diabetes Endocrinol 2, 810-818.

  • Francioli, L.C., Consortium, T.G.o.t.N., Menelaou, A., Pulit, S.L., van Dijk, F., Palamara, P.F., Elbers, C.C., Neerincx, P.B.T., Ye, K., Guryev, V., et al. (2014). Whole-genome sequence variation, population structure and demographic history of the Dutch population. Nature Genetics 46, 818-825.

  • Gaalen van, J., de Swart, B.J.M., Oostveen, J., Knuijt, S., van de Warrenburg, B.P.C., and Kremer, B.P.H. (2014a). Language Impairment in Cerebellar Ataxia. Movement Disorders 29, 1307-1312.

  • Gaalen van, J., Kerstens, F.G., Maas, R.P.P.W., Harmark, L., and van de Warrenburg, B.P.C. (2014b). Drug-Induced Cerebellar Ataxia: A Systematic Review. CNS Drugs 28, 1139-1153.

  • Ghoussaini, M., Edwards, S.L., Michailidou, K., Nord, S., Cowper-Sal Lari, R., Desai, K., Kar, S., Hillman, K.M., Kaufmann, S., Glubb, D.M., et al. (2014). Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulation. Nature Communications 5, no 4999.

  • Gils van, A., Janssens, K.A.M., and Rosmalen, J.G.M. (2014). Family disruption increases functional somatic symptoms in late adolescence: The TRAILS Study. Health Psychology 33, 1354-1361.

  • Groot de, M.C.H., de Bruijn, W., van Grootheest, G., Klungel, O.H., and Smit, J.H. (2014). Inventarisatie van koppelwensen en mogelijkheden van biobanken en databanken in Nederland (BBMRI-NL; Biolink project).

  • Guadalupe, T., Willems, R.M., Zwiers, M.P., Arias Vasquez, A., Hoogman, M., Hagoort, P., Fernandez, G., Buitelaar, J., Franke, B., Fisher, S.E., et al. (2014a). Differences in cerebral cortical anatomy of left- and right-handers. Frontiers in Psychology 28, 261.

  • Guadalupe, T., Zwiers, M.P., Teumer, A., Wittfeld, K., Vasquez, A.A., Hoogman, M., Hagoort, P., Fernandez, G., Buitelaar, J., Hegenscheid, K., et al. (2014b). Measurement and genetics of human subcortical and hippocampal asymmetries in large datasets. Human Brain Mapping 35, 3277-3289.

  • Heemskerk-Gerritsen, B.A.M., Rookus, M.A., Aalfs, C.M., Ausems, M.G.E.M., Collé, J.M., Jansen, L., Kets, C.M., Keymeulen, K.B.M.I., Koppert, L.B., Meijers-Heijboer, H.E.J., et al. (2014). Improved overall survival after contralateral risk-reducing mastectomy in BRCA1/2 mutation carriers with a history of unilateral breast cancer: A prospective analysis. International Journal of Cancer 136, 668-677.

  • Hoeijen van, D.A., Blom, M.T., and Tan, H.L. (2014). Cardiac sodium channels and inherited electrophysiological disorders: an update on the pharmacotherapy. Expert Opinion on Pharmacotherapy 15, 1875-1887.

  • Hoffland, B.S., Veugen, L.C., Janssen, M.M.H.P., Pasman, J.W., Weerdesteyn, V., and van de Warrenburg, B.P. (2014). A gait paradigm reveals different patterns of abnormal cerebellar motor learning in primary focal dystonias. Cerebellum 13, 760-766.

  • Holmes, M.V., Dale, C.E., Zuccolo, L., Silverwood, R.J., Guo, Y., Ye, Z., Prieto-Merino, D., Dehghan, A., Trompet, S., Wong, A., et al. (2014). Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data. BMJ British Medical Journal 349.

  • Hoogman, M., Guadalupe, T., Zwiers, M.P., Klarenbeek, P., Francks, C., and Fisher, S.E. (2014). Assessing the effects of common variation in the FOXP2 gene on human brain structure. Frontiers in Human Neuroscience 8, 473.

  • Howat, W.J., Blows, F.M., Provenzano, E., Brook, M.N., Morris, L., Gazinska, P., Johnson, N., McDuffus, L., Miller, J., Sawyer, E., et al. (2014). Performance of automated scoring of ER, PR, HER2, CK5/6 and EGFR in breast cancer tissue microarrays in the Breast Cancer Association Consortium. Journal of Pathology: Clinical Research 1, 18-32.

  • Huppertz, C., Bartels, M., Groen-Blokhuis, M., Dolan, C.V., de Moor, M.H.M., Abdellaoui, A., van Beijsterveldt, C.E.M., Ehli, E.A., Hottenga, J.J., Willemsen, G., et al. (2014). The dopaminergic reward system and leisure time exercise behavior: a candidate allele study. Biomed Research International 2014, no 591717.

  • Iles, M.M., Bishop, D.T., Taylor, J.C., Hayward, N.K., Brossard, M., Cust, A.E., Dunning, A.M., Lee, J.E., Moses, E.K., Akslen, L.A., et al. (2014). The effect on melanoma risk of genes previously associated with telomere length. J National Cancer Institute 106, 5.

  • Iterson van, M., Tobi, E.W., Slieker, R.C., den Hollander, W., Luijk, R., Slagboom, P.E., and Heijmans, B.T. (2014). MethylAid: visual and interactive quality control of large Illumina 450k datasets. Bioinformatics 30, 3435-3437.

  • Jansen, R., Batista, S., Brooks, A.I., Tischfield, J.A., Willemsen, G., van Grootheest, G., Hottenga, J.J., Milaneschi, Y., Mbarek, H., Madar, V., et al. (2014). Sex differences in the human peripheral blood transcriptome. BMC Genomics 15, 33.

  • Janssens, K.A.M., Klis, S., Kingma, E.M., Oldehinkel, A.J., and Rosmalen, J.G.M. (2014a). Predictors for persistence of functional somatic symptoms in adolescents. J Pediatr 164, 900-905.e902.

  • Janssens, K.A.M., Oldehinkel, A.J., Bonvanie, I.J., and Rosmalen, J.G.M. (2014b). An inactive lifestyle and low physical fitness are associated with functional somatic symptoms in adolescents. The TRAILS study. Journal of Psychosomatic Research 76, 454-457.

  • Jiang, X., Trouw, L.A., van Wesemael, T.J., Shi, J., Bengtsson, C., Kallberg, H., Malmstrom, V., Israelsson, L., Hreggvidsdottir, H., Verduijn, W., et al. (2014). Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies. Annals of the Rheumatic Diseases 73, 1761-1768.

  • Jong de, K., Vonk, J.M., Kromhout, H., Vermeulen, R., Postma, D.S., and Boezen, H.M. (2014). NOS1: a susceptibility gene for reduced level of FEV1 in the setting of pesticide exposure. American journal of respiratory and critical care medicine 190, 1188-1190.

  • Jonker, I., Klein, H.C., Duivis, H.E., Yolken, R.H., Rosmalen, J.G.M., and Schoevers, R.A. (2014). Association between Exposure to HSV1 and Cognitive Functioning in a General Population of Adolescents. The TRAILS Study. PLoS One 9, e101549.

  • Khan, S., Greco, D., Michailidou, K., Milne, R.L., Muranen, T.A., Heikkinen, T., Aaltonen, K., Dennis, J., Bolla, M.K., Liu, J., et al. (2014). MicroRNA related polymorphisms and breast cancer risk. PLoS One 9, e109973.

  • Knaap van der, L.J., Riese, H., Hudziak, J.J., Verbiest, M.M.P.J., Verhulst, F., Oldehinkel, A.J., and Van Oort, F.V.A. (2014a). Glucocorticoid receptor gene (NR3C1) methylation following stressful events between birth and adolescence. The TRAILS study. Translational Psychiatry 4.

  • Knaap van der, L.J., Schaefer, J.M., Franken, I.H.A., Verhulst, F.C., van Oort, F.V.A., and Riese, H. (2014b). Catechol-O-methyltransferase gene methylation and substance use in adolescents: the TRAILS study. Genes, Brain and Behavior 13, 618-625.

  • Knevel, R., Klein, K., Somers, K., Ospelt, C., Houwing-Duistermaat, J.J., van Nies, J.A., de Rooy, D.P., de Bock, L., Kurreeman, F.A., Schonkeren, J., et al. (2014). Identification of a genetic variant for joint damage progression in autoantibody-positive rheumatoid arthritis. Ann Rheum Dis 73, 2038-2046.

  • Knoppers, B.M., Harris, J.R., Budin-Ljosne, I., and Dove, E.S. (2014). A human rights approach to an international code of conduct for genomic and clinical data sharing. Human Genetics 133, 895-903.

  • Korhonen, T., Loukola, A., Wedenoja, J., Nyman, E., Latvala, A., Broms, U., Happola, A., Paunio, T., Schrage, A.J., Vink, J.M., et al. (2014). Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder. PLoS One 9, e98199.

  • Kretschmer, T., Sentse, M., Dijkstra, J.K., and Veenstra, R. (2014). The Interplay Between Peer Rejection and Acceptance in Preadolescence and Early Adolescence, Serotonin Transporter Gene, and Antisocial Behavior in Late Adolescence: The TRAILS Study. Journal of Developmental Psychology 60, 193-216.

  • Kuchenbaecker, K.B., Neuhausen, S.L., Robson, M., Barrowdale, D., McGuffog, L., Mulligan, A.M., Andrulis, I.L., Spurdle, A.B., Schmidt, M.K., Schmutzler, R.K., et al. (2014). Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers. Breast Cancer Research 16, 3416.

  • Kurki, M.I., Gaal, E.I., Kettunen, J., Lappalainen, T., Menelaou, A., Anttila, V., van 't Hof, F.N.G., von und zu Fraunberg, M., Helisalmi, S., Hiltunen, M., et al. (2014). High risk population isolate reveals low frequency variants predisposing to intracranial aneurysms. PLoS Genetics 10, e1004134.

  • Laceulle, O.M., Aken van, M.A.G., Ormel, J., and Nederhof, E. (2014a). Stress-sensitivity and reciprocal associations between stressful events and adolescent temperament. Personality and Individual Differences 81, 76-83.

  • Laceulle, O.M., Nederhof, E., van Aken, M.A., and Ormel, J. (2014b). Adolescent Personality: Associations With Basal, Awakening, and Stress-Induced Cortisol Responses. Journal of Personality 83, 262-273.

  • Laceulle, O.M., Ormel, J., Vollebergh, W.A.M., van Aken, M.A.G., and Nederhof, E. (2014c). A test of the vulnerability model: temperament and temperament change as predictors of future mental disorders - the TRAILS study. Journal of Child Psychology and Psychiatry 55, 227-236.

  • Lacko, M., Braakhuis, B.J.M., Sturgis, E.M., Boedeker, C.C., Suárez, C., Rinaldo, A., Ferlito, A., and Takes, R.P. (2014). Genetic Susceptibility to Head and Neck Squamous Cell Carcinoma. International Journal of Radiation Oncology*Biology*Physics 89, 38-48.

  • Leeuwen van, A.P., Creemers, H.E., Verhulst, F.C., Vollebergh, W.A.M., Ormel, J., van Oort, F., and Huizink, A.C. (2014a). Legal substance use and the development of a DSM-IV cannabis use disorder during adolescence: the TRAILS study. Addiction 109, 303-311.

  • Leeuwen van, E.M., Smouter, F.A., Kam-Thong, T., Karbalai, N., Smith, A.V., Harris, T.B., Launer, L.J., Sitlani, C.M., Li, G., Brody, J.A., et al. (2014b). The challenges of genome-wide interaction studies: lessons to learn from the analysis of HDL blood levels. PLoS One 9, e109290.

  • Leeuwen van, N., Beekman, M., Deelen, J., van den Akker, E.B., de Craen, A.J.M., Slagboom, P.E., and 't Hart, L.M. (2014c). Low mitochondrial DNA content associates with familial longevity: the Leiden Longevity Study. Age 36, 9629.

  • Li, J., Lindstrom, L.S., Foo, J.N., Rafiq, S., Schmidt, M.K., Pharoah, P.D., Michailidou, K., Dennis, J., Bolla, M.K., Wang, Q., et al. (2014). 2q36.3 is associated with prognosis for oestrogen receptor-negative breast cancer patients treated with chemotherapy. Nature Communications 17, 4051.

  • Lien van, R., Neijts, M., Willemsen, G., and de Geus, E.J. (2014). Ambulatory measurement of the ECG T-wave amplitude. Psychophysiology 52, 225-237.

  • Lin, W.Y., Camp, N.J., Ghoussaini, M., Beesley, J., Michailidou, K., Hopper, J.L., Apicella, C., Southey, M.C., Stone, J., Schmidt, M.K., et al. (2014). Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk. Human Molecular Genetics 24, 285-298.

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