Publications 2015

We have listed only items that contain BBMRI-NL or the grant number in the affiliation, funding and/or acknowledgement section of the article. Items are listed per year in alphabetical order.

  • Abdellaoui A, Hottenga JJ, Willemsen G, Bartels M, van Beijsterveldt T, Ehli EA, Davies GE, Brooks A, Sullivan PF, Penninx BWJH, et al.: Educational attainment influences levels of homozygosity through migration and assortative mating. PLoS One 10(3): e0118935.
  • Abdellaoui A, Ehli EA, Hottenga JJ, Weber Z, Mbarek H, Willemsen G, van Beijsterveldt T, Brooks A, Hudziak JJ, Sullivan PF, et al.: CNV concordance in 1,097 MZ twin pairs. Twin Research and Human Genetics 18(1): 1-12.
  • Akker van den EB, Deelen J, Slagboom PE, Beekman M. Exome and whole genome sequencing in aging and longevity. In “Longevity genes: A blueprint for aging” 2015: 127-139, Springer New York.
  • Bardai A, Blom MT, van Noord C, Verhamme KM, Sturkenboom MCJM, Tan HL: Sudden cardiac death is associated both with epilepsy and with use of antiepileptic medications. Heart 101(1): 17-22.
  • Barrett JH, Taylor JC, Bright C, Harland M, Dunning AM, Akslen LA, Andresen PA, Avril MF, Azizi E, Scarra GB, et al.: Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions. International Journal of Cancer 136(6): 1351-1360.
  • Baselmans BML, van Dongen J, Nivard MG, Lin BD, Zilhao NR, Boomsma DI, Bartels M, BIOS Consortium: Epigenome-wide association study of wellbeing. Twin Research and Human Genetics 18(6): 710-719.
  • Bastiaansen JA, van Roon AM, Buitelaar JK, Oldehinkel AJ: Mental health problems are associated with low-frequency fluctuations in reaction time in a large general population sample. The trails study. European Psychiatry 30(2): 347-353.
  • Bastiaansen JA, Cummins TDR, Riese H, van Roon AM, Nolte IM, Oldehinkel AJ, Bellgrove MA: A population based study of the genetic association between catecholamine gene variants and spontaneous low-frequency fluctuations in reaction time. PLoS One 10(5): e0126461.
  • Beek van JHDA, Lubke GH, de Moor MHM, Willemsen G, de Geus EJC, Hottenga JJ, Walters RK, Smit JH, Penninx BWJH, Boomsma DI, et al.: Heritability of liver enzyme levels estimated from genome-wide snp data. European Journal of Human Genetics 23(9): 1223-1228.
  • Berentzen NE, van Stokkom VL, Gehring U, Koppelman GH, Schaap LA, Smit HA, Wijga AH: Associations of sugar-containing beverages with asthma prevalence in 11-year-old children: The piama birth cohort. European Journal of Clinical Nutrition 69(3): 303-308.
  • Blanco I, Kuchenbaecker K, Cuadras D, Wang XS, Barrowdale D, de Garibay GR, Librado P, Sanchez-Gracia A, Rozas J, Bonifaci N, et al.: Assessing associations between the aurka-hmmr-tpx2-tubg1 functional module and breast cancer risk in brca1/2 mutation carriers. PLoS One 10(4): e0120020.
  • Blein S, Bardel C, Danjean V, McGuffog L, Healey S, Barrowdale D, Lee A, Dennis J, Kuchenbaecker KB, Soucy P, et al.: An original phylogenetic approach identified mitochondrial haplogroup t1a1 as inversely associated with breast cancer risk in brca2 mutation carriers. Breast Cancer Research 17: 61.
  • Blom MT, Jansen S, de Jonghe A, van Munster BC, de Boer A, de Rooij SE, Tan HL, van der Velde N: In-hospital haloperidol use and perioperative changes in qtc-duration. Journal of Nutrition Health & Aging 19(5): 583-589.
  • Boeckhout M, Douglas CM: Governing the research-care divide in clinical biobanking: Dutch perspectives. Life Sci Soc Policy 11: 7.
  • Boekel N, Schaapveld M, van Leeuwen FE. Using record linkage to construct a population-based cancer patient cohort with multiple disease outcomes. Part i: Methods and experiences from the Netherlands cancer institute in the construction of a populationbased breast cancer survivor cohort linked with cardiovascular disease and mortality registries: AvL; 2015.
  • Boelema SR, Harakeh Z, van Zandvoort MJE, Reijneveld SA, Verhulst FC, Ormel J, Vollebergh WAM: Adolescent heavy drinking does not affect maturation of basic executive functioning: Longitudinal findings from the trails study. PLoS One 10(10): e0139186.
  • Bonvanie IJ, van Gils A, Janssens KAM, Rosmalen JGM: Sexual abuse predicts functional somatic symptoms: An adolescent population study. Child Abuse & Neglect 46: 1-7.
  • Bonvanie IJ, Rosmalen JGM, van Rhede van der Kloot CM, Oldehinkel AJ, Janssens KAM: Short report: Functional somatic symptoms are associated with perfectionism in adolescents. Journal of Psychosomatic Research 79(4): 328-330.
  • Booij SH, Bos EH, de Jonge P, Oldehinkel AJ: Markers of stress and inflammation as potential mediators of the relationship between exercise and depressive symptoms: Findings from the trails study. Psychophysiology 52(3): 352-358.
  • Bot M, Milaneschi Y, Penninx BWJH, Drent ML: Association of plasma insulin-like growth factor-1 with depressive and anxiety disorders, and antidepressant medication use. Biological Psychiatry 77(9): 2.
  • Bot M, Chan MK, Jansen R, Lamers F, Vogelzangs N, Steiner J, Leweke FM, Rothermundt M, Cooper J, Bahn S, et al.: Serum proteomic profiling of major depressive disorder. Translational Psychiatry 5: e599.
  • Bot M, Chan MK, Jansen R, Lamers F, Vogelzangs N, Steiner J, Leweke FM, Rothermundt M, Cooper J, Bahn S, et al.: Serum proteomic profiling of major depressive disorder. Biological Psychiatry 77(9): 332S-332S.
  • Broer L, van Duijn CM: Gwas and meta-analysis in aging/longevity. Adv Exp Med Biol 847: 107-125.
  • Brouwer E, Arends S, Bootsma H, Roozendaal C, Limburg PC, Maas F, Toes REM, Huizinga TWJ, Trouw LA, Van Zanten A: Presence of ACPA in a large (> 40.000) population based cohort from the netherlands. Arthritis & Rheumatology 67: 2.
  • Chen J, Calhoun VD, Arias-Vasquez A, Zwiers MP, van Hulzen K, Fernandez G, Fisher SE, Franke B, Turner JA, Liu J: G-protein genomic association with normal variation in gray matter density. Hum Brain Mapp 36(11): 4272-4286.
  • Deelen P, Zhernakova DV, de Haan M, van der Sijde M, Bonder MJ, Karjalainen J, van der Velde KJ, Abbott KM, Fu J, Wijmenga C, et al.: Calling genotypes from public rna-sequencing data enables identification of genetic variants that affect gene-expression levels. Genome Medicine 7(1 - eCollection 2015): 30.
  • Demirkan A, Henneman P, Verhoeven A, Dharuri H, Amin N, van Klinken JB, Karssen LC, de Vries B, Meissner A, Goraler S, et al.: Insight in genome-wide association of metabolite quantitative traits by exome sequence analyses. PLoS Genet 11(1): e1004835.
  • Dongen van J, Nivard MG, Baselmans BML, Zilhao NR, Ligthart L, Heijmans BT, Bartels M, Boomsma DI, BIOS Consortium: Epigenome-wide association study of aggressive behavior. Twin Research and Human Genetics 18(6): 686-698.
  • Draisma HHM, Pool R, Kobl M, Jansen R, Petersen AK, Vaarhorst AAM, Yet I, Haller T, Demirkan A, Esko T, et al.: Genome-wide association study identifies novel genetic variants contributing to variation in blood metabolite levels. Nature Communications 6: 7208.
  • Elten van TM, van Rossem L, Wijga AH, Brunekreef B, de Jongste JC, Koppelman GH, Smit HA: Breast milk fatty acid composition has a long-term effect on the risk of asthma, eczema, and sensitization. Allergy 70(11): 1468-1476.
  • Engelhardt EG, Kriege M, Hooning MJ, Seynaeve C, Tollenaar R, van Asperen CJ, Ausems MGEM, van de Poll-Franse L, Mook S, Verhoef S, et al.: Familial versus sporadic breast cancer: Different treatments for similar tumors? Advances in Breast Cancer Research 4: 87-99.
  • Fagerholm R, Schmidt MK, Khan S, Rafiq S, Tapper W, Aittomaki K, Greco D, Heikkinen T, Muranen TA, Fasching PA, et al.: The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients. Oncotarget 6(10): 7390-7407.
  • Fall T, Hagg S, Ploner A, Magi R, Fischer K, Draisma HHM, Sarin AP, Benyamin B, Ladenvall C, Akerlund M, et al.: Age- and sex-specific causal effects of adiposity on cardiovascular risk factors. Diabetes 64(5): 1841-1852.
  • Fallon SJ, Smulders K, Esselink RA, van de Warrenburg BP, Bloem BR, Cools R: Differential optimal dopamine levels for set-shifting and working memory in Parkinson’s disease. Neuropsychologia 77: 42- 51.
  • Fedko IO, Hottenga JJ, Medina-Gomez C, Pappa I, van Beijsterveldt CEM, Ehli EA, Davies GE, Rivadeneira F, Tiemeier H, Swertz MA, et al.: Estimation of genetic relationships between individuals across cohorts and platforms: Application to childhood height. Behavior Genetics 45(5): 514-528.
  • Francioli LC, Polak PP, Koren A, Menelaou A, Chun S, Renkens I, The Genome of the Netherlands Consortium, van Duijn CM, Swertz MA, Wijmenga C, et al.: Genome-wide patterns and properties of de novo mutations in humans. Nature Genetics 47(7): 822-826.
  • Francois M, Schaefer JM, Bole-Feysot C, Dechelotte P, Verhulst FC, Fetissov SO: Ghrelin-reactive immunoglobulins and anxiety, depression and stress-induced cortisol response in adolescents. The TRAILS study. Progress in Neuro-Psychopharmacology & Biological Psychiatry 59: 1-7.
  • Franic S, Groen-Blokhuis MM, Dolan CV, Kattenberg MV, Pool R, Xiao XJ, Scheet PA, Ehli EA, Davies GE, van der Sluis S, et al.: Intelligence: Shared genetic basis between Mendelian disorders and a polygenic trait. European Journal of Human Genetics 23(10): 1378-1383.
  • Fuertes E, Soderhall C, Acevedo N, Becker A, Brauer M, Chan-Yeung M, Dijk FN, Heinrich J, de Jongste J, Koppelman GH, et al.: Associations between the 17q21 region and allergic rhinitis in 5 birth cohorts. J Allergy and Clinical Immunology 135(2): 573-576.
  • Gottlieb DJ, Hek K, Chen TH, Watson NF, Eiriksdottir G, Byrne EM, Cornelis M, Warby SC, Bandinelli S, Cherkas L, et al.: Novel loci associated with usual sleep duration: The CHARGE consortium genome-wide association study. Molecular Psychiatry 20(10): 1232- 1239.
  • Grady BP, Prins M, Rebers S, Molenkamp R, Geskus RB, Schinkel J: BMI, male sex and IL28b genotype associated with persistently high hepatitis c virus RNA levels among chronically infected drug users up to 23 years following seroconversion. J Viral Hepatitis 22(3): 263- 271.
  • Grootheest van G, de Groot M, van der Laan SW, Smit J, Bakker B. Record linkage for health studies: Three demonstration projects. Statistics Netherlands: 2015.
  • Guadalupe T, Zwiers MP, Wittfeld K, Teumer A, Vasquez AA, Hoogman M, Hagoort P, Fernandez G, Buitelaar J, van Bokhoven H, et al.: Asymmetry within and around the human planum temporale is sexually dimorphic and influenced by genes involved in steroid hormone receptor activity. Cortex 62(SI): 41-55.
  • Guo XY, Long JR, Zeng CJ, Michailidou K, Ghoussaini M, Bolla MK, Wang Q, Milne RL, Shu XO, Cai QY, et al.: Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk. Cancer Epidemiology Biomarkers & Prevention 24(11): 1680-1691.
  • Guo Q, Schmidt MK, Kraft P, Canisius S, Chen C, Khan S, Tyrer J, Bolla MK, Wang Q, Dennis J, et al.: Identification of novel genetic markers of breast cancer survival. J National Cancer Institute 107(5): 9.
  • Gutierrez-Achury J, Zorro MM, Ricano-Ponce I, Zhernakova DV, Consortium CDI, Consortium R, Diogo D, Raychaudhuri S, Franke L, Trynka G, et al.: Functional implications of disease-specific variants in loci jointly associated with coeliac disease and rheumatoid arthritis. Human Molecular Genetics 25(1): 180-190.
  • Heemskerk-Gerritsen BAM, Seynaeve C, Van Asperen CJ, Ausems MGEM, Collee JM, van Doorn HC, Gomez Garcia EB, Kets CM, van Leeuwen FE, Meijers-Heijboer HEJ, et al.: Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: Revisiting the evidence for risk reduction. JNCI - Journal of the National Cancer Institute 107(5): djv033.
  • Heininga VE, Oldehinkel AJ, Veenstra R, Nederhof E: I just ran a thousand analyses: Benefits of multiple testing in understanding equivocal evidence on gene-environment interactions. PLoS One 10(5): e0125383.
  • Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivieres S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, et al.: Common genetic variants influence human subcortical brain structures. Nature 520(7546): 224-229.
  • Hiltemann S, Jenster G, Trapman J, van der Spek P, Stubbs A: Discriminating somatic and germline mutations in tumor DNA samples without matching normals. Genome Research 25(9): 1382- 1390.
  • Hochner H, Allard C, Granot-Hershkovitz E, Chen JB, Sitlani CM, Sazdovska S, Lumley T, McKnight B, Rice K, Enquobahrie DA, et al.: Parent-of-origin effects of the APOb gene on adiposity in young adults. PLoS Genetics 11(10): e1005573.
  • Hoeijen van DA, Blom MT, Bardai A, Souverein PC, de Boer A, Tan HNL: Reduced pre-hospital and in-hospital survival rates after out-ofhospital cardiac arrest of patients with type-2 diabetes mellitus: An observational prospective community-based study. Europace 17(5): 753-760.
  • Hofman A, Brusselle GGO, Murad SD, van Duijn CM, Franco OH, Goedegebure A, Ikram MA, Klaver CCW, Nijsten TEC, Peeters RP, et al.: The Rotterdam study: 2016 objectives and design update. European Journal of Epidemiology 30(8): 661-708.
  • Horikoshi M, Mgi R, van de Bunt M, Surakka I, Sarin AP, Mahajan A, Marullo L, Thorleifsson G, Hgg S, Hottenga JJ, et al.: Discovery and fine-mapping of glycaemic and obesity-related trait loci using highdensity imputation. PLoS Genet 11(7): e1005230.
  • Ikram MA, van der Lugt A, Niessen WJ, Koudstaal PJ, Krestin GP, Hofman A, Bos D, Vernooij MW: The Rotterdam scan study: Design update 2016 and main findings. European Journal of Epidemiology 30(12): 1299-1315.
  • Jacobi H, du Montcel ST, Bauer P, Giunti P, Cook A, Labrum R, Parkinson MH, Durr A, Brice A, Charles P, et al.: Long-term disease progression in spinocerebellar ataxia types 1, 2, 3, and 6: A longitudinal cohort study. Lancet Neurology 14(11): 1101-1108.
  • Jacobs LC, Hamer MA, Gunn DA, Deelen J, Lall JS, van Heemst D, Uh HW, Hofman A, Uitterlinden AG, Griffiths CEM, et al.: A genomewide association study identifies the skin color genes IRF4, MC1r, ASIP, and BNC2 influencing facial pigmented spots. Journal of Investigative Dermatology 135(7): 1735-1742.
  • Jagt-Jelsma van der W, de Vries-Schot MR, de Jong R, Hartman CA, Verhulst FC, Klip H, van Deurzen PA, Buitelaar JK: Religiosity and mental health of pre-adolescents with psychiatric problems and their parents: The TRAILS study. Eur Psychiatry 30(7): 845-851.
  • Jamal M, van der Does W, Penninx BWJH: Effect of variation in BDNF val(66)met polymorphism, smoking, and nicotine dependence on symptom severity of depressive and anxiety disorders. Drug and Alcohol Dependence 148: 150-157.
  • Jamal M, van der Does W, Elzinga BM, Molendijk ML, Penninx BWJH: Association between smoking, nicotine dependence, and BDNF val66met polymorphism with BDNF concentrations in serum. Nicotine & Tobacco Research 17(3): 323-329.
  • Jamshidi M, Fagerholm R, Khan S, Aittomaki K, Czene K, Darabi H, Li J, Andrulis IL, Chang-Claude J, Devilee P, et al.: SNP-SNP interaction analysis of NF-kappa b signaling pathway on breast cancer survival. Oncotarget 6(35): 37979-37994.
  • Jansen H, Wijga AH, Scholtens S, Koppelman GH, Postma DS, Brunekreef B, de Jongste JC, Smit HA, Stolk RP: Change in HbA1c levels between the age of 8 years and the age of 12 years in Dutch children without diabetes: The PIAMA birth cohort study. PLoS One 10(4): e0119615.
  • Jensen RA, Sim X, Smith AV, Li X, Jakobsdottir J, Cheng CY, Brody JA, Cotch MF, McKnight B, Klein R, et al.: Novel genetic loci associated with retinal microvascular diameter. Circ Cardiovasc Genet 9(1): 45- 54.
  • Jong de K, Vonk JM, Timens W, Bosse Y, Sin DD, Hao K, Kromhout H, Vermeulen R, Postma DS, Boezen HM: Genome-wide interaction study of gene-by-occupational exposure and effects on FEV1 levels. Journal of Allergy and Clinical Immunology 136(6): 1664- 1672.e1614.
  • Kaakinen M, Claringbould A, Hagenbeek F, Magi R, Soininen P, Jarvelin MR, Morris A, Prokopenko I, BIOS Consortium: Genome-wide multiphenotype and eQTL analyses provide novel insights into omega fatty acid metabolism. Human Heredity 80(3): 115.
  • Kabisch M, Bermejo JL, Duennebier T, Ying SB, Michailidou K, Bolla MK, Wang Q, Dennis J, Shah M, Perkins BJ, et al.: Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer. Carcinogenesis 36(2): 256-271.
  • Kanterakis A, Kuiper J, Potamias G, Swertz MA: Pypedia: Using the wiki paradigm as crowd sourcing environment for bioinformatics protocols. Source Code Biol Med 10(eCollection): 14.
  • Kanterakis A, Deelen P, van Dijk F, Byelas H, Dijkstra M, Swertz MA: Molgenis-impute: Imputation pipeline in a box. BMC Res Notes 8: 359.
  • Kato N, Loh M, Takeuchi F, Verweij N, Wang X, Zhang WH, Kelly TN, Saleheen D, Lehne B, Leach IM, et al.: Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation. Nature Genetics 47(11): 1282-1293.
  • Kendler KS, Aggen SH, Li Y, Lewis CM, Breen G, Boomsma DI, Bot M, Penninx BWJH, Flint J: The similarity of the structure of DSM-IV criteria for major depression in depressed women from china, the united states and europe. Psychological Medicine 45(9): 1945-1954.
  • Klein M, van der Voet M, Harich B, van Hulzen KJ, Onnink AM, Hoogman M, Guadalupe T, Zwiers M, Groothuismink JM, Verberkt A, et al.: Converging evidence does not support GIT1 as an ADHD risk gene. Am J Med Genet B Neuropsychiatr Genet 168(6): 492- 507.
  • Klijs B, Scholtens S, Mandemakers JJ, Snieder H, Stolk RP, Smidt N: Representativeness of the lifelines cohort study. PLoS One 10(9): e0137203.
  • Kloosterman WP, Francioli LC, Hormozdiari F, Marschall T, Hehir-Kwa JY, Abdellaoui A, Lameijer EW, Moed MH, Koval V, Renkens I, et al.: Characteristics of de novo structural changes in the human genome. Genome Research 25(6): 792-801.
  • Knaap van der LJ, Oldehinkel AJ, Verhulst FC, van Oort FVA, Riese H: Glucocorticoid receptor gene methylation and HPA-axis regulation in adolescents. The TRAILS study. Psychoneuroendocrinology 58: 46-50.
  • Knaap van der LJ, van Oort FVA, Verhulst FC, Oldehinkel AJ, Riese H: Methylation of NR3C1 and SLC6A4 and internalizing problems. The TRAILS study. Journal of Affective Disorders 180: 97-103.
  • Knaap van der LJ, Riese H, Hudziak JJ, Verbiest MMPJ, Verhulst FC, Oldehinkel AJ, van Oort FVA: Adverse life events and allele-specific methylation of the serotonin transporter gene (SLC6A4) in adolescents: The TRAILS study. Psychosomatic Medicine 77(3): 246- 255.
  • Koek M, Achterberg H, de Groot M, Vast E, Klein S, Niessen W: Population imaging study IT infrastructure: An automated continuous workflow approach. MAnagement and Processing of images for Population ImagiNG, Munich: 2015.
  • Kolder ICRM, Tanck MWT, Postema PG, Barc J, Sinner MF, Zumhagen S, Husemann A, Stallmeyer B, Koopmann TT, Hofman N, et al.: Analysis for genetic modifiers of disease severity in patients with long-QT syndrome type 2. Circulation - Cardiovascular Genetics 8(3): 447-456.
  • Kupers LK, Xu XL, Jankipersadsing SA, Vaez A, la Bastide-van Gemert S, Scholtens S, Nolte IM, Richmond RC, Relton CL, Felix JF, et al.: DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring. International Journal of Epidemiology 44(4): 1224-1237.
  • Laurin CA, Hottenga JJ, Willemsen G, Boomsma DI, Lubke GH: Genetic analyses benefit from using less heterogeneous phenotypes: An illustration with the hospital anxiety and depression scale (HADS). Genetic Epidemiology 39(4): 317-324.
  • Leeuwen van EM, Kanterakis A, Deelen P, Kattenberg MV, Slagboom PE, de Bakker PI, Wijmenga C, Swertz MA, Boomsma DI, van Duijn CM, et al.: Population-specific genotype imputations using minimac or IMPUTE2. Nature Protocols 10(9): 1285-1296.
  • Leeuwen van EM, Karssen LC, Deelen J, Isaacs A, Medina-Gomez C, Mbarek H, Kanterakis A, Trompet S, Postmus I, Verweij N, et al.: Genome of the Netherlands population-specific imputations identify an ABCA6 variant associated with cholesterol levels. Nature Communications 6: 6065.
  • Lei J, Rudolph A, Moysich KB, Rafiq S, Behrens S, Goode EL, Pharoah PP, Seibold P, Fasching PA, Andrulis IL, et al.: Assessment of variation in immunosuppressive pathway genes reveals TGFBR2 to be associated with prognosis of estrogen receptor-negative breast cancer after chemotherapy. Breast Cancer Research 17: 18.
  • Lin BD, Mbarek H, Willemsen G, Dolan CV, Fedko IO, Abdellaoui A, de Geus EJ, Boomsma DI, Hottenga JJ: Heritability and genome-wide association studies for hair color in a Dutch twin family based sample. Genes 6(3): 559-576.
  • Linneberg A, Jacobsen RK, Skaaby T, Taylor AE, Fluharty ME, Jeppesen JL, Bjorngaard JH, Aring;svold BO, Gabrielsen ME, Campbell A, et al.: Effect of smoking on blood pressure and resting heart rate: A Mendelian randomization meta-analysis in the CARTA consortium. Circulation - Cardiovascular Genetics 8(6): 832-841.
  • Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S, Buchkovich ML, Yang J, et al.: Genetic studies of body mass index yield new insights for obesity biology. Nature 518(7538): 197-206.
  • Lubke GH, Ouwens KG, de Moor MHM, Trull TJ, Boomsma DI: Population heterogeneity of trait anger and differential associations of trait anger facets with borderline personality features, neuroticism, depression, attention deficit hyperactivity disorder (ADHD), and alcohol problems. Psychiatry Research 230(2): 553- 560.
  • Luijk R, Goeman JJ, Slagboom PE, Heijmans BT, van Zwet EW: An alternative approach to multiple testing for methylation QTL mapping reduces the proportion of falsely identified CPGs. Bioinformatics 31(3): 340-345.
  • Maas RP, van Gaalen J, Klockgether T, van de Warrenburg BPC: The preclinical stage of spinocerebellar ataxias. Neurology 85(1): 96- 103.
  • Malik R, Freilinger T, Anttila V, Vander Heiden J, Traylor M, de Vries B, Holliday EG, Terwindt GM, Sturm J, Bis JC, et al.: Shared genetic basis for migraine and ischemic stroke: A genome-wide analysis of common variants. Neurology 84(21): 2132-2145.
  • Mavaddat N, Pharoah PDP, Michailidou K, Tyrer J, Brook MN, Bolla MK, Wang Q, Dennis J, Dunning AM, Shah M, et al.: Prediction of breast cancer risk based on profiling with common genetic variants. JNCI - Journal of the National Cancer Institute 107(5): djv036.
  • Mbarek H, Milaneschi Y, Fedko IO, Hottenga JJ, de Moor MHM, Jansen R, Gelernter J, Sherva R, Willemsen G, Boomsma DI, et al.: The genetics of alcohol dependence: Twin and SNP-based heritability, and genome-wide association study based on audit scores. American Journal of Medical Genetics Part B-Neuropsychiatric Genetics 168(8): 739-748.
  • Minica CC, Dolan CV, Hottenga JJ, Pool R, Fedko IO, Mbarek H, Huppertz C, Bartels M, Boomsma DI, Vink JM, et al.: Heritability, SNP- and gene-based analyses of cannabis use initiation and age at onset. Behavior Genetics 45(5): 503-513.
  • Moor de MHM, van den Berg SM, Verweij KJH, Krueger RF, Luciano M, Vasquez AA, Matteson LK, Derringer J, Esko T, Amin N, et al.: Metaanalysis of genome-wide association studies for neuroticism, and the polygenic association with major depressive disorder. Jama Psychiatry 72(7): 642-650.
  • Morris RW, Taylor AE, Fluharty ME, Bjorngaard JH, Asvold BO, Gabrielsen ME, Campbell A, Marioni R, Kumari M, Korhonen T, et al.: Heavier smoking may lead to a relative increase in waist circumference: Widence for causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium. BMJ Open 5(8): 10.
  • Mostert JC, Hoogman M, Onnink AM, van Rooij D, von Rhein D, van Hulzen KJ, Dammers J, Kan CC, Buitelaar JK, Norris DG, et al.: Similar subgroups based on cognitive performance parse heterogeneity in adults with ADHD and healthy controls. J Atten Disord 3: 281-292.
  • Mostert JC, Onnink AMH, Klein M, Dammers J, Harneit A, Schulten T, van Hulzen KJE, Kan CC, Slaats-Willemse D, Buitelaar JK, et al.: Cognitive heterogeneity in adult attention deficit/hyperactivity disorder: A systematic analysis of neuropsychological measurements. European Neuropsychopharmacology 25(11): 2062- 2074.
  • Müller H, Reihs R, Zatloukal K, Jeanquartier F, Merino-Martinez R, van Enckevort D, Swertz MA, Holzinger A. State-of-the-art and future challenges in the integration of biobank catalogues. In: “Smart health: Open problems and future challenges” 2015: 261-273, Springer International Publishing.
  • Nederhof E, van Oort FVA, Bouma EMC, Laceulle OM, Oldehinkel AJ, Ormel J: Predicting mental disorders from hypothalamic-pituitaryadrenal axis functioning: A 3-year follow-up in the trails study. Psychological Medicine 45(11): 2403-2412.
  • Nyholt D, Draisma H, Yang Y, Ligthart L, Boomsma DI: Association of genetic factors influencing serum metabolites with genetic risk for migraine. Cephalalgia 35(Suppl. 6): 260.
  • Ocke MC, Feskens EJM, van Dongen MCJM, Bueno de Mesquita HB, van’t Veer P, Dagnelie PC: Introduction on food frequency questionnaires and the BBMRI FFQ project. The European Congress of Epidemiology 2015: 739.
  • Ocke M, Eussen S, Geelen A, Brants H, van Dongen M, de Vries J, Bueno de Mesquita B, Dagnelie P, Feskens E: Development, validation and backward compatibility of FFQ-NL1.0, a new food frequency questionnaire for the Netherlands. Annals of Nutrition and Metabolism 67: 227-227.
  • Oh G, Wang SC, Pal M, Chen ZF, Khare T, Tochigi M, Ng C, Yang YA, Kwan A, Kaminsky ZA, et al.: DNA modification study of major depressive disorder: Beyond locus-by-locus comparisons. Biological Psychiatry 77(3): 246-255.
  • Oldehinkel AJ, Ormel J: A longitudinal perspective on childhood adversities and onset risk of various psychiatric disorders. European Child & Adolescent Psychiatry 24(6): 641-650.
  • Oldehinkel AJ, Hartman CA, van Oort FV, Nederhof E: Emotion recognition specialization and context-dependent risk of anxiety and depression in adolescents. Brain and Behavior 5(2): e00299.
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